DNA damage assessment of Hela cancer cell line by biosynthetic zinc oxide nanoparticles

The current study examined the genotoxic effect of biosynthetic zinc oxide nanoparticles ZnONPs using Vitex agnus-castus plant, which contains effective compounds that inhibit growth pure cancer cells. phenotypic and structural characteristics biosynthesized were detected scanning electron microscopy (SEM). Most dense spherical with sizes ranging from (20-61) nanometers, on cervical cell line Hela compared normal Human Foreskin Fibroblast cells (HFF) green dye. Comet assay technique genotoxicity experiments carried out at Iraqi Center for Cancer Research / Al-Mustansiriya University. results this showed presence damage to DNA Hela, stopped division entry. Cells are in stage programmed death a result release reactive oxygen radicals (ROS) changing functions by linking nanomaterial genetic material. This gives hope discovering successful treatment eliminate or any type methods Biosynthesis nanoparticles.